Best NMN Supplement 2025: Our Top 3 Picks

Nicotinamide mononucleotide (NMN), is one of the most exciting compounds to debut on the market in decades. It is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for various cellular processes. Supplementing with NMN offers several potential benefits, particularly related to aging and overall health:

  • Metabolic Health: Increased NAD+ levels can improve metabolic functions, aiding in weight management and reducing the risk of metabolic disorders like diabetes.
  • Sirtuin Activation: NAD+ activates sirtuins, a family of proteins associated with longevity and protection against age-related diseases.
  • DNA Repair: Enhanced NAD+ levels help repair DNA damage, a key factor in the aging process.
  • Neuroprotection: NMN supplementation may protect against neurodegenerative diseases by improving mitochondrial function and reducing oxidative stress.
  • Heart Health: Enhanced mitochondrial function and reduced oxidative stress improve heart health.
  • Exercise Performance: NMN can improve muscle endurance and strength by enhancing mitochondrial function and energy production.
  • Muscle Repair: Increased NAD+ levels aid in muscle repair and recovery.
  • Immune Response: NMN may support a healthy immune system by improving the function of immune cells and reducing inflammation.
  • Extended Lifespan: Studies suggest that NMN supplementation may extend lifespan and improve healthspan by mitigating age-related decline in cellular functions.
  • Glucose Metabolism: NMN may enhance insulin sensitivity and improve glucose metabolism, reducing the risk of insulin resistance and type 2 diabetes.

Deciding which NMN product is right for you can be difficult with all the different options available. So, we put together a short list of the top 3 best NMN supplements we tested, and recommend:

Overall Winner: 

1. AEON NAD+ Longevity Complex by Perpetua Life Biotech ($59-$47)

AEON NAD+ Longevity Supplement

AEON contains a combo of NMN and NR bound in a Liposomal formula that increases its absorption by up to 300% (study: PMID36014827).

But that’s not all! AEON includes 9 other ingredients that all follow Dr. David Sinclair’s longevity protocol including:

Resveratrol, Quercetin, Fisetin, TMG, Spermidine, EGCG, Astragalus, Piperine, and L-Theanine.

All of these ingredients are also in liposomal form. Furthermore, Piperine has been shown to increase the absorption of antioxidants like resveratrol by up to 1500% (Study: PMID21714124), which makes AEON the best choice for those who’re looking for a powerful all-in-one longevity supplement.

The company making AEON,Perpetua Life Biotech, is also a full-blown research & development firm with an impressive medical board of MD/PhD’s from around the globe. Their products are all developed, sourced, and manufactured in-house in the United States. All their facilities are also NSF/GMP audited, and FDA registered to ensure consistent quality.

If you choose AEON feel free to use our coupon code HEALTH for an additional 10% off your order at Perpetua.Life.

2. NMN Pro™ Complete ($114-$79)

Pro Health

Pro Health’s NMN Pro is a balanced combination of NMN, Trans-reveratrol, and TMG.

  • Unique Trio of Longevity-Supporting Ingredients at High Doses. NMN Pro Complete is a perfectly balanced combination of NMN, Trans-Resveratrol and TMG. Instead of having to take three separate supplements each day, you can now get the ideal balance of all three in one convenient serving.
  • New Capsule Form. For people who don’t want to take powdered supplements, capsules are an easy, convenient, and portable way to get your NMN.
  • Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

If you choose Pro Health’s NMN feel free to use coupon code HEALTH for an additional 10% off your order.

3. TruNiagen NR 300mg  ($40-$49)

TruNiagen

Tru Niagen is a supplement that contains nicotinamide riboside (NR),  a patented form of vitamin B3 that helps cells produce nicotinamide adenine dinucleotide (NAD+). 

Tru Niagen is backed by over 300 published scientific studies, 40 patents, and 275 global research collaborations, and is also acknowledged as safe by the FDA and NSF-certified for sport. Some say they feel great after taking Tru Niagen, and that it’s helped them have more energy and look forward to being active. 

However, WebMD notes that nicotinamide riboside chloride can cause mild side effects such as nausea, bloating, itching, and sweating, especially when taken in doses higher than 300mg per day.

If you choose TruNiagen feel free to use our coupon HEALTH for an additional 10% off your order.

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